AHK-Cu

AHK-Cu

AHK-CuDermatology
CAS: 682809-81-0
MF: C15H24ClCuN6O4
MW: 451.39
Indications
Commonly used in cosmetic products for the skin and hair
Therapeutic Target
Usage

An efficient ingredient combats hair loss by strengthening hair follicle structure through stimulating key protein synthesis and providing antioxidant protection to repair the scalp and delay follicular aging.

Specification
>99%
Product Description

Overview

AHK-Cu (Copper Peptide 1) is a highly efficient ingredient renowned for its distinctive blue color and exceptional bioactivity. Through multi-targeted mechanisms, it addresses the root causes of hair loss by effectively restoring the scalp environment and promoting the growth of healthy, strong hair. Its core benefits include: acting as a signaling peptide to stimulate the synthesis of key proteins such as collagen, thereby strengthening the follicle structure; providing powerful antioxidant protection to neutralize free radicals and delay follicular aging; and repairing damaged scalp while improving barrier health to create an optimal growth environment for hair follicles. It is widely used in scalp care products such as hair growth serums and anti-hair loss shampoos.

Synonyms: ALA-HIS-LYS-CU; Copper Peptide 1:1; L-Alanyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]copper Monohydrochloride; AHK-Cu(2:1); ALA-HIS-LYS-CU(AHK-Cu)

Mol File: 682809-81-0.mol

Physicochemical Properties

Storage condition: Store at cool dry place(-20°C, away from the light)  


MSDS Information

Experimental Data

Pharmacodynamics

Mechanism Of Action

This copper-binding tripeptide (Alanine-Histidine-Lysine-Copper) is researched for skin and hair regeneration. Its mechanism involves chelating copper ions to enhance enzymatic reactions, stimulating fibroblast proliferation, boosting vascular endothelial growth factor (VEGF) for angiogenesis, and promoting collagen, elastin, and extracellular matrix production. It also increases antioxidant enzyme activity to reduce oxidative damage, supports wound healing, and may influence TGF-beta1 pathways to activate cell replication in hair follicles.