Procapil

Procapil

ProcapilDermatology
CAS: 299157-54-3
MF: C24H38N8O6S
MW: 566.67
Indications
Therapeutic Target
Amyloid-β
Usage

Improves follicle microcirculation, inhibits 5α-reductase, and reduces follicle miniaturization and fibrosis; widely used in shampoos, conditioners, scalp sprays, and daily anti-hair loss products.

Specification
>99%
Product Description

Overview

Procapil is a world-renowned patented anti-hair loss complex combining Biotinoyl Tripeptide-1, Apigenin, and Oleanolic Acid, celebrated for its “triple-action” multi-target mechanism. It comprehensively improves follicle microcirculation, potently inhibits 5α-reductase, and significantly reduces follicular fibrosis, known as the “natural non-hormonal alternative to minoxidil + finasteride.” Its core benefits include strengthening follicle anchorage, resisting DHT attack, reversing miniaturization, and being gentle with no irritation. Extensively used in daily shampoos, conditioners, scalp sprays, and anti-hair loss sprays.

Synonyms: BiotinoylTripeptide-1; BIO-GHK; biotinoyltripeptide; widelash; Biotinoylglycylhistidyllysine; Biotinyl-GHKtripeptide; N-[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]glycyl-L-histidyl-L-lysine

EINECS: 000-000-0

Product Categories: Botanical Complex; 5α-Reductase Inhibitors; Peptide & Flavonoid Combinations; Follicle Anchorage Enhancers; Anti-Follicular Fibrosis Agents

Mol File: 299157-54-3.mol

Physicochemical Properties

Boiling point: 1128.5±65.0 °C(Predicted)

Density: 1.321±0.06 g/cm3(Predicted)

Storage temp.: Store at -20°C

Solubility: DMSO: 5mg/mL; PBS (pH 7.2): 10mg/mL

Form: Solid

Color: White to off-white

MSDS Information

Experimental Data

1.Cell Experiment

Solubility in DMSO: 87.5 mg/mL (154.41 mM; solubilized with ultrasound; the solubility of the product is significantly affected by hygroscopic DMSO, so please use freshly opened DMSO)

Preparing Stock Solutions:

image

Please choose an appropriate solvent to prepare the stock solution based on the product's solubility in different solvents. Once the solution is prepared, aliquot and store it to avoid product degradation caused by repeated freeze-thaw cycles.

Storage conditions and shelf life of the stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). Use within 6 months when stored at -80°C, and within 1 month when stored at -20℃.

Pharmacodynamics


Mechanism Of Action