3-aminopiperidine-2,6-dione hydrochloride
Used as a pharmaceutical intermediate; used as a key building block in the synthesis of Lenalidomide.
Overview
3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del (5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. Moreover, it is also a metabolite of thalidomide (T338850) that inhibits FGF-induced angiogenesis.
Synonyms: 2,6-Dioxopiperidine-3-ammonium chloride;2,6-Dioxopiperidine-3-ammonium;Lenalidomide Impurity 6 HCl;Pomalidomide/lenalidomide INT II;3-Amino-piperidine-2,6-dione [2353-44-8] at 262 USD, please be noted, what we provide is HCl salt form;2,6-dioxopiperidin-3-aminium chloride;Pomalidomide Impurity 6;6-piperidinedione hydrochloride
EINECS: 807-866-6
Product Categories: Pyrrolidines
Mol File: 24666-56-6.mol
Physicochemical Properties
Boiling point: 120°C
Storage temp: Inert atmosphere,Room Temperature
Solubility: DMSO (Slightly, Heated), Methanol (Sparingly, Sonicated)
Form: Powder
Color: White