4-nitroisobenzofuran-1,3-dione

4-Nitroisobenzofuran-1,3-dione serves as a key intermediate in synthesizing benzimidazole PARP inhibitors like ABT-472. It reacts with aminoquinazolinones to form phthalimidoquinazolinone derivatives through cyclization reactions, demonstrating its crucial role in constructing complex heterocyclic scaffolds for anticancer drug development.

Synonyms: 1,3-Isobenzofurandione, 4-nitro-;1,3-Isobenzofurandione,4-nitro-;3-Isobenzofurandione,4-nitro-1;NSC 4134;3-Nitrophthalic anhydride, synthesis grade;4-Nitrobenzo[c]furan-1,3-dione, 4-Nitro-2-benzofuran-1,3-dione, 4-Nitroisobenzofuran-1,3-dione;3-Nitrophthalic anhydride,97%;Phthalic anhydride, 3-nitro- (6CI,7CI,8CI)

EINECS: 211-373-6

Product Categories: Anhydride Monomers;Monomers;Polymer Science;Carbonyl Compounds;Carboxylic Acid Anhydrides;Organic Building Blocks;Amines;Aromatics;Intermediates;Building Blocks;Carbonyl Compounds;Carboxylic Acid Anhydrides;Chemical Synthesis;Organic Building Blocks;Phthalic Acids, Esters and Derivatives;Dyes intermediates

Mol File: 641-70-3.mol