4-Nitrobenzyl chloride
Used for organic synthesis and pharmaceutical intermediates; used to prepare unsymmetrically N,N′-bis(substituted) 4,13-diaza-18-crown-6-ether derivatives.
Overview
4-Nitrobenzyl chloride is a key organic intermediate widely used in synthesizing pharmaceutical compounds. It serves as a crucial building block for antibiotics like chloramphenicol and various antitumor agents, primarily through alkylation reactions and protecting carboxyl groups in complex synthetic routes.
Synonyms: P-NITROBENZYLCHLORIDE;α-Chloro-4-nitrotoluene;Nitrobenzylchloride;p-Nitrobenzylchloride4-NitrobenzylchloriChemicalbookde;p-nitrochloride;à-chloro-4-nitrotoluene;ALPHA-CHLORO-PARA-NITROTOLUENE;TOLUENE,ALPHA-CHLORO-PARA-NITRO-
EINECS: 202-822-7
Product Categories: Nitro and nitroso compounds; Other biochemical reagents; Biochemical reagents; Aromatic hydrocarbons; Organic building blocks; Aromatic halides (substituted)
Mol File: 100-14-1.mol
Physicochemical Properties
Melting point: 71℃
Boiling point: 112°C (0.6 mmHg)
Solubility: chloroform: soluble50mg/mL, clear to very slightly hazy, faintly yellow
Form: Crystalline Needles or Powder
Color: Light yellow
Stability: Stable. Incompatible with strong oxidizing agents, bases, amines, moisture, alcohols. Corrodes steel. Reacts slowly with water. Combustible.