tert-butyl (S)-(1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl)carbamate

tert-Butyl (S)-(1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl)carbamate serves as a key chiral intermediate in developing cathepsin C inhibitors. This iodophenyl-containing building block undergoes sequential Boc deprotection and amidation reactions to construct the essential peptide-mimetic core structure of therapeutic agents. Its molecular architecture, featuring both protected amine and iodinated aromatic functionalities, enables precise structural modifications for developing targeted inhibitors with enhanced enzymatic selectivity and pharmacological properties in pharmaceutical research.

Synonyms: (S)-tert-butyl (1-aMino-3-(4-iodophenyl)-1-oxopropan-2-yl)carbaMate; (S)-tert-butyl (1-aMino-3-(4-iodophenyl)-1-oxopropan-2-yl)carbaMate;S-[1-Carbamoyl-2-(4-iodo-phenyl)-ethyl]-carbamic acid tert-butyl ester;Carbamic acid, N-[(1S)-2-amino-1-[(4-iodophenyl)methyl]-2-oxoethyl]-, 1,1-dimethylethyl ester

Mol File: 868694-44-4.mol