3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one

3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one serves as a versatile boronic ester intermediate in pharmaceutical research and development. This specialized building block undergoes Suzuki-Miyaura cross-coupling reactions with various aryl halides to construct complex biaryl structures essential for drug discovery. It finds particular application in developing kinase inhibitors and other therapeutic agents, where its benzo[d]oxazolone core provides optimal molecular geometry for target binding while the boronic ester functionality enables efficient carbon-carbon bond formation. The compound's unique combination of heterocyclic scaffold and boron-based reactivity makes it particularly valuable for creating focused libraries of drug-like molecules with enhanced pharmacological properties.

Synonyms:3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(3H)-benzoxazolone; 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(3H)-benzoxazolone;2(3H)-Benzoxazolone, 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazol-2(3H)-one;3-Methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-ylboronic Acid Pinacol Ester;3-Methyl-2-oxo-2,3-dihydrobenzo[d]oxazole-5-boronic Acid Pinacol Ester;3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazol-2-one;3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[dJoxazol- 2(3H)-one

Mol File: 1220696-32-1.mol