tert-butyl piperidin-4-ylcarbamate
Used as a versatile pharmaceutical building block for the synthesis of piperidine-based CCR5 antagonists with anti-HIV-1 activity, peripherally selective cannabinoid receptor antagonists, and as an amino-functionalization reagent for polymers.
Overview
4-(N-Boc-amino)piperidone may be used as a functionalization reagent for introduction of a primary and a tertiary amino group to poly(2-isopropyl-2-oxazoline. It can also be used as pharma building block. It is used in the synthesis of a piperidine-4-carboxamide CCR5 antagonist with potent anti-HIV 1-activity. It is an intermediate for the synthesis of various pharmaceutical and biologically active compounds, including inhibitors and therapeutic agents. It is used for the synthesis of diphenyl purine derivatives as peripherally selective cannabinoid receptor 1 Antagonists.
Synonyms: 4-N-BOC-Aminopiperidine;4-(TERT-BUTOXYCARBONYLAMINO)PIPERIDINE;4-N-TERT-BOC-AMINO PIPERIDINE;4-N-(TERT-BUTOXYCARBONYL)AMINOPIPERIDINE;4-BOC-AMINOPIPERIDINE;4-AMINOPIPERIDINE, 4-BOC PROTECTED;4-(N-BOC-AMINO)PIPERIDINE;4-(tert-ButoxycarbonylaMino)piperidine, 98.0%(GC&T;CARBAMIC ACID, 4-PIPERIDINYL-, 1,1-DIMETHYLETHYL ESTER
EINECS: 616-026-6
Product Categories: Pyrans, Piperidines & Piperazines;Building Blocks;Pyridine series;Pyrans, Piperidines &Piperazines;Piperidines;Heterocyclic Building Blocks;Amines;blocks;pharmacetical;Piperidine
Mol File: 73874-95-0.mol
Physicochemical Properties
Melting point: 162-166°C
Boiling point: 80°C/0.05mm
Storage temp: Keep in dark place,Sealed in dry,Room Temperature
Solubility: Soluble in Methanol
Form: Crystalline Powder
Color: Off-white