2-chloro-6-methoxy-3-nitropyridine

2-Chloro-6-methoxy-3-nitropyridine serves as a key synthetic intermediate in the preparation of novel antibacterial agents, particularly for the synthesis of Gepotidacin, a first-in-class triazaacenaphthylene antibiotic targeting bacterial topoisomerases. This halogenated nitropyridine derivative undergoes crucial Suzuki and Negishi cross-coupling reactions to construct the core scaffold of the drug molecule, while also serving as a precursor for 6-methoxy-3-nitropyridine-2-carbonitrile through cyanation reactions. Its versatile reactivity enables precise molecular modifications essential for developing antibiotics against drug-resistant bacterial strains.

Synonyms: 2-Chloro-6-methoxy-3-nitropyridine ,98%;Pyridine, 2-chloro-6-methoxy-3-nitro-;2-Choro-3-nitro-6-methoxypyridine;2-CHLORO-3-NITRO-METHOXYPYRIDINE;2-chloro-3-aMino-6-Methoxypyridine;2-CHLORO-3-NITRO-6-METHOXYPYRIDINE;2-CHLORO-6-METHOXY-3-NITROPYRIDINE;2-CHLORO-6-METHOXY-(3 OR 5)-NITROPYRIDINE

EINECS: 253-989-8

Product Categories: Heterocycle-Pyridine series;blocks;Pyridines;Pyridine;Chloropyridines;Halopyridines;compounds of pyridine;Pyridine series;Halides;C6Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;alkyl chloride|nitro-compound

Mol File: 38533-61-8.mol