2-fluoro-4-iodoaniline
Used as a pharmaceutical intermediate; used as a fundamental building block in the chemical industry to prepare various important compounds.
Overview
2-Fluoro-4-iodoaniline (29632-74-4) serves as a key intermediate in synthesizing Mirdametinib, a MEK inhibitor for cancer treatment. This halogenated aniline derivative undergoes Suzuki-Miyaura cross-coupling and sequential amidation reactions to construct the essential aniline core structure, enabling precise development of targeted anticancer therapeutics with enhanced kinase selectivity.
Synonyms: 2-FLUORO-4-IODOANILINE;2-FLUORO-4-IODOBENZENAMINE;2-Fluoro-4-idioaniline;2-FLUORO-4-IODO-PHENYLAMINE;2-Fluoro-4-iodoaniline 98%;2-Fluoro-4-iodoaniline98%;2-Fluoro-4-iodoanili;2-fluo-4-iodoaniline
Product Categories: Benzenes;Amines;Fluorobenzene;Fluoro-Aromatics;C2 to C6;Nitrogen Compounds;Benzene series;Aniline;Miscellaneous;Anilines, Amides & Amines;Fluorine Compounds;Iodine Compounds;amine| alkyl Fluorine| alkyl Iodine;bc0001
Mol File: 29632-74-4.mol
Physicochemical Properties
Melting point: 55-57°C
Boiling point: 248.6±25.0°C
Storage temp: Keep in dark place,Sealed in dry,Room Temperature
Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Water Solubility: insoluble
Form: Powder
Color: Off-white to brown