3,6-dichloro-4-isopropylpyridazine
Used as a chlorinated pyridazine compound and organic synthesis intermediate for the preparation of heterocyclic compounds.
Overview
3,6-Dichloro-4-isopropylpyridazine serves as a key synthetic intermediate for Resmetirom and other heterocyclic compounds. This chlorinated pyridazine derivative undergoes selective nucleophilic aromatic substitution reactions, enabling precise construction of the core heterocyclic scaffold essential for developing thyroid hormone receptor beta agonists to treat metabolic diseases.
Synonyms: 3,6-dichloro-4-isopropylpyridazine;Pyridazine, 3,6-dichloro-4-(1-methylethyl)-;3,6-DICHLORO-4-ISOPROPYLPYRIDAZINE(WXG00195);3,6-dichloro-4-(propan-2-yl)pyridazine;3,6-Dichloro-4-(1-methylethyl)pyridazine;Rui Si Mei Ti Luo Impurity 1;3,6-dichloro-4-isopropylpyridazine - [D16389]
EINECS: 200-533-0
Mol File: 107228-51-3.mol
Physicochemical Properties
Boiling point: 278.7±35.0°C
Storage temp: -20°C, sealed storage, away from moisture